Unless Virt improves his cycle game, I don't really think he would have chemistry with Hank. The Sedins would be at their own blue line with the puck while Jake is already a zone ahead of them. The speed difference is immense. I know they have chemistry with the Honey Badger but he can cycle the puck very well, in addition to being lightning quick.
Like you said, he would need a centre who excels on the rush, someone like Monahan, Carter, Giroux, or Johnson.
Tank 4 Matthewz maybe??????