TOMapleLaughs Posted March 4, 2015 Share Posted March 4, 2015 Eat all you want? Don't excercise? Don't gain weight? Even eliminate diabetes?Newly discovered hormone mimics the effects of exercise Scientists at the USC Leonard Davis School of Gerontology have discovered a new hormone that fights the weight gain caused by a high-fat Western diet and normalizes the metabolism -- effects commonly associated with exercising. Hormones are molecules that act as the body's signals, triggering various physiological responses. The newly discovered hormone, dubbed "MOTS-c," primarily targets muscle tissue, where it restores insulin sensitivity, counteracting diet-induced and age-dependent insulin resistance. "This represents a major advance in the identification of new treatments for age-related diseases such as diabetes," said Pinchas Cohen, dean of the USC Davis school and senior author of a study on the research, which will appear in Cell Metabolism on March 3. To test the effects of MOTS-c, the team injected the hormone into mice fed a high-fat diet, which typically causes them to grow obese and develop a resistance to insulin. The injections not only suppressed both effects in mice, they also reversed age-dependent insulin-resistance, a condition that precedes diabetes. "This discovery sheds new light on mitochondria and positions them as active regulators of metabolism," said Changhan Lee, assistant professor at USC Davis and lead author of the study. MOTS-c is unique among hormones in that it is encoded in the DNA of mitochondria -- the "powerhouses" of cells that convert food into energy. Other hormones are encoded in DNA in the nucleus. Lee and Cohen collaborated with colleagues from the USC school as well as the David Geffen School of Medicine at UCLA and the National Institutes of Health. While all of the experiments on MOTS-c to date have been performed on lab mice, the molecular mechanisms that make it function in mice exist in all mammals, including humans. The MOTS-c intellectual property has been licensed to a biotechnology company, and clinical trials in humans could begin within the next three years, Cohen said. http://www.sciencedaily.com/releases/2015/03/150303183407.htm The future is going to be sweet. Assuming this transfers over and the side-effects aren't drastic in humans, this awesome news for big pharma, sugar companies, McDonalds, etc. Very bad news for gyms, personal trainers, etc. Link to comment Share on other sites More sharing options...
drummer4now Posted March 4, 2015 Share Posted March 4, 2015 Eat all you want? Don't excercise? Don't gain weight? Even eliminate diabetes?http://www.sciencedaily.com/releases/2015/03/150303183407.htm The future is going to be sweet. Assuming this transfers over and the side-effects aren't drastic in humans, this awesome news for big pharma, sugar companies, McDonalds, etc.Very bad news for gyms, personal trainers, etc. Gyms aren't just meant for fat people... There are some that go to get swole. Link to comment Share on other sites More sharing options...
Rey Posted March 4, 2015 Share Posted March 4, 2015 Good. Now i can marry a sexy wife, then sue her ass if we have a fat baby and win. Link to comment Share on other sites More sharing options...
aGENT Posted March 4, 2015 Share Posted March 4, 2015 Oh good Link to comment Share on other sites More sharing options...
Baka Posted March 4, 2015 Share Posted March 4, 2015 Good. Now i can marry a sexy wife, then sue her ass if we have a fat baby and win. What if it's a sexy fat baby? Link to comment Share on other sites More sharing options...
Aladeen Posted March 4, 2015 Share Posted March 4, 2015 Just make it mandatory in all fast food and Obese problem solved! Link to comment Share on other sites More sharing options...
Hobble Posted March 4, 2015 Share Posted March 4, 2015 So it allows the muscles to take up more glucose and store it as glycogen, and stimulates protein synthesis, encouraging muscle growth? Link to comment Share on other sites More sharing options...
thejazz97 Posted March 4, 2015 Share Posted March 4, 2015 What happens if you receive this hormone and work out? Do you turn into the Rock? Link to comment Share on other sites More sharing options...
avelanch Posted March 4, 2015 Share Posted March 4, 2015 Link to comment Share on other sites More sharing options...
Heretic Posted March 4, 2015 Share Posted March 4, 2015 Please add that to beer. Link to comment Share on other sites More sharing options...
Dazzle Posted March 4, 2015 Share Posted March 4, 2015 This hormone's going to be banned in pro sports. Link to comment Share on other sites More sharing options...
thejazz97 Posted March 4, 2015 Share Posted March 4, 2015 This hormone's going to be banned in pro sports. Everything is banned in pro sports. Link to comment Share on other sites More sharing options...
avelanch Posted March 4, 2015 Share Posted March 4, 2015 This hormone's going to be banned in pro sports. how would they tell? it's naturally occurring in the body, especially in pro athletes who exercise all the time, and would be used up fairly quickly by the body i would imagine. Link to comment Share on other sites More sharing options...
Hobble Posted March 4, 2015 Share Posted March 4, 2015 Or does this not affect muscle mass at all, and just allow our metabolism to handle higher fat diets? Because the article doesn't mention anything about muscle mass. Essentially, it just increases your metabolism, just like exercise would, but it doesn't replace all the effects of exercise, like actual muscle strengthening. Link to comment Share on other sites More sharing options...
hsedin33 Posted March 4, 2015 Share Posted March 4, 2015 Eat all you want? Don't excercise? Don't gain weight? Even eliminate diabetes?http://www.sciencedaily.com/releases/2015/03/150303183407.htm The future is going to be sweet. Assuming this transfers over and the side-effects aren't drastic in humans, this awesome news for big pharma, sugar companies, McDonalds, etc. Very bad news for gyms, personal trainers, etc. Very bad news for personal trainers and gyms? Doubtful. Does this hormone also lower cholesterol? Give you good nutrition? Fat isn't the problem, malnutrition is the problem. You still have to eat right and train to get lean and muscular, sorry. Link to comment Share on other sites More sharing options...
Captain Aerosex Posted March 4, 2015 Share Posted March 4, 2015 how would they tell? it's naturally occurring in the body, especially in pro athletes who exercise all the time, and would be used up fairly quickly by the body i would imagine. So is testosterone, they're able to test for abnormal level, ratios (though the tests can of course be beaten). I don't know how they could do it, but I'm sure they could find a way to do it. Link to comment Share on other sites More sharing options...
TOMapleLaughs Posted March 5, 2015 Author Share Posted March 5, 2015 Very bad news for personal trainers and gyms? Doubtful. Does this hormone also lower cholesterol? Give you good nutrition? Fat isn't the problem, malnutrition is the problem. You still have to eat right and train to get lean and muscular, sorry.That was before the newly discovered hormone that mimics the effects of exercise though. Of course gyms and personal trainers will see less business, just as viagra affected the penis pump industry, lol. Link to comment Share on other sites More sharing options...
Green Building Posted March 5, 2015 Share Posted March 5, 2015 Very bad news for personal trainers and gyms? Doubtful. Does this hormone also lower cholesterol? Give you good nutrition? Fat isn't the problem, malnutrition is the problem. You still have to eat right and train to get lean and muscular, sorry. Exactly. At best it will allow unhealthy people to potentially hide their poor lifestyle for a time. Concurrently, there is a peculiar spike in heart disease. edit: This does offer some very practical applications for people suffering from obesity and diabetes though, and I wonder how long it will be before someone does a study on how much money can be saved by the health care industry by reducing visits to hospitals and doctors for at risk folk who take the hormone. Link to comment Share on other sites More sharing options...
FramingDragon Posted March 5, 2015 Share Posted March 5, 2015 Don't see it as an excuse to not lift. Link to comment Share on other sites More sharing options...
Hobble Posted March 5, 2015 Share Posted March 5, 2015 People will still go to gyms to be fit. This hormone doesn't build muscle. Link to comment Share on other sites More sharing options...
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