Yes definitely pros and cons for aisles. Always easy access, but you do need to stand up more to let people in and out etc.
I have row 10 aisles in the UB and there are tons of leg room ,as there are no one directly in front of my two seats. Aisle seats also seem to have better resale value.
Besides the railing, the clear glass on top of the section entrances also sometimes gets in the way