Jump to content
The Official Site of the Vancouver Canucks
Enter Search Term. Use arrows to navigate between autocomplete results. If no results appear, use Enter to do a full site search.
Forum Closure ×
Canucks Community
Forum Closure

Coronavirus outbreak

CBH1926

By CBH1926
in Off-Topic General

 Share

Recommended Posts

UnkNuk Canucks Third-Line

UnkNuk

Posted
Posted
10 hours ago, Wolfgang Durst said:

What is in the best interest of countries and societies all over the world? Is it a cheap vaccine that has an efficacy of around 60% based on clinical trials or is it a more expensive vaccine with an efficacy of 95%?

We all know the answer: we have to contain COVID 19 in order to get back to normal life. In order to get to this point we need vaccines with a high efficacy, like the ones from BioNTech/Pfizer and Moderna (both around 95% efficacy) , or even Novavax with 89%.

UK might feel great because of the high availability of the AZ vaccine and the high speed of the vaccination. In the end of the day there is a good chance that COVID 19 will come back in the UK and they have to impose lockdowns with negative effects on the economy and people's life again. 

 

Just imagine, the EMA - counterpart of Health Canada - couldn't put an efficacy rate on the vaccine for older age groups. They stated in their report "protection is expected" for those age groups. Good luck to those people. 

 

I would opt for BioNTech/Pfizer, Moderna and the Novavax vaccine anytime. Prices per dose for BioNTech/Pfizer and Moderna leaked several months ago. A politician from either Belgium or the Netherlands - can't recall exactly- revealed the prices by accident. Price per dose for BioNTech/Pfizer was - if I recall correctly 12,20 Euro - and price per dose for Moderna was - if I recall correctly - 14,60 or 14,80 Euro. Yes, vaccine of AZ is insanely cheap with approximately 2,00 Euro - that's the number I have read couple of months ago in a newspaper. If I were a politician and therefore responsible for the welfare of society I would opt for BioNTech/Pfizer and Moderna.

 

 

 

I agree that, given a choice between a vaccine with a 95% efficacy and a vaccine with a 60% efficacy, everyone will want the vaccine  with a 95% efficacy.

 

But what if the choice is between a cheap vaccine that has an efficacy of around 60% and no vaccine at all?   That may be the choice facing many third world countries.

 

Again, I find it remarkable that a pharma company would sell their product at cost.  (And, again, I'm assuming the AZ vaccine is being sold at cost - there's some debate about that.)  

 

  • Upvote 1
Link to comment
Share on other sites
UnkNuk Canucks Third-Line

UnkNuk

Posted
Posted

Of course.         :sadno:

 

************************************************************************************************

https://theprovince.com/news/criminal-rings-are-selling-fake-covid-19-test-certificates-at-international-airports-police-warn/wcm/130be529-8008-4b72-bdbb-8694646199e5/?utm_source=Sailthru&utm_medium=email&utm_campaign=VANSUNPROV COVID 19 Newsletter 2021-02-01&utm_term=SUNPROV COVID19 Newsletter

 

Criminal rings are selling fake COVID-19 test certificates at international airports, police warn

 

As if there isn’t enough worry over international travel and emerging variants of COVID-19, European police are warning that fraudulent test certificates are being sold to international travellers to skirt pandemic restrictions.

 

Illicit sales of fake certificates declaring passengers have tested negative for COVID-19 have been uncovered in Britain, France, Spain and the Netherlands, resulting in arrests, including some inside airports.

Link to comment
Share on other sites
stawns Canucks Hall-of-Famer

stawns

Posted
Posted
48 minutes ago, UnkNuk said:

Of course.         :sadno:

 

************************************************************************************************

https://theprovince.com/news/criminal-rings-are-selling-fake-covid-19-test-certificates-at-international-airports-police-warn/wcm/130be529-8008-4b72-bdbb-8694646199e5/?utm_source=Sailthru&utm_medium=email&utm_campaign=VANSUNPROV COVID 19 Newsletter 2021-02-01&utm_term=SUNPROV COVID19 Newsletter

 

Criminal rings are selling fake COVID-19 test certificates at international airports, police warn

 

As if there isn’t enough worry over international travel and emerging variants of COVID-19, European police are warning that fraudulent test certificates are being sold to international travellers to skirt pandemic restrictions.

 

Illicit sales of fake certificates declaring passengers have tested negative for COVID-19 have been uncovered in Britain, France, Spain and the Netherlands, resulting in arrests, including some inside airports.

If you get caught with one of those, you should be subject to the strictest punishment possible under the law

  • Upvote 3
Link to comment
Share on other sites
Russ Canucks Regular

Russ

Posted
Posted
On 1/31/2021 at 2:35 PM, Silent Man said:

Thank you for the link

This is a very upsetting information, really.

“UK vaccinate 200 people a minute” We can only dream about this.

“UK started pandemic with 0 production capacity to produce vaccine. We built everything during last 8-9 months. We took that decision last spring to actually have this capability” What our government was doing last spring?

This interview just confirmed my thoughts that our government failed miserably to response to this pandemic

Hard to compare.  Major Pizer plant is in Belgium so it is easier to transport there, plus England was the first I can remember that started buying up as many doses as possible, it was a couple weeks later when Canada was like "oh yea so maybe we should buy some"

 

Also 200 people a minute, when it takes 8 hours to drive from bottom to top of the country essentially, its really easy to get people in for vaccines.  Heck we can't even get to calgary in 11 hours or prince george or any of the very other remote areas so distriubuting and having people file in is going to be far faster and easier.  Not giving government a lifeline here but logistically its going to be way harder and slower in a giant country. 

Link to comment
Share on other sites
Gurn Canucks Hall-of-Famer

Gurn

Posted
Posted

Canada,  helping rebuild the vaccine industry at home:

https://www.msn.com/en-ca/news/canada/canada-signs-deal-with-novavax-to-make-its-covid-19-vaccine-at-new-montreal-facility/ar-BB1djn32?ocid=msedgntp

OTTAWA — Prime Minister Justin Trudeau says Canada has signed a tentative agreement for Novavax to produce millions of doses of its COVID-19 vaccine in Canada once it's approved for use here.

The U.S. company is still doing clinical trials of its vaccine but if Health Canada approves it, a new National Research Council facility in Montreal will begin pumping out Novavax doses when the building is finished later this year.

 

It would be the first COVID-19 vaccine to be produced domestically.

Canada is currently at the mercy of foreign governments, which could at any time slam the doors shut to vaccine exports until their own people are vaccinated.

That risk becomes ever more real this week as Europe's new export controls on vaccines take hold, putting at risk Canada's entire supply of COVID-19 vaccines.

Trudeau also says additional vaccines could be produced in Saskatchewan and Vancouver, but there are no deals with other vaccine makers to use those facilities yet.

The University of Saskatchewan’s Vaccine and Infectious Disease Organization, which received a $46-million funding boost from Ottawa last year, could now produce 40 million doses a year, and Precision NanoSystems in Vancouver, which got a federal grant of $23 million, can produce 240 million doses.

The deal could help Trudeau tamp down the political headache caused by Canada's skeletal vaccine production capacity.

But Novavax's vaccine is likely at least two months away from being approved in Canada, while the NRC facility is still under construction and designed to produce only about two million doses a month. Canada has a deal to buy 52 million doses from Novavax after it is approved by Health Canada.

All doses from the currently approved vaccines being produced by Pfizer-BioNTech and Moderna are being made in Europe.

Maryland-based Novavax applied Friday to start the regulatory review process for its experimental vaccine, after announcing a clinical trial in the United Kingdom showed it was more than 89 per cent effective against COVID-19.

The trial in the U.K. showed significant effectiveness against both the original virus behind COVID-19, and the variant known as B.1.17 that was first identified there. A smaller Phase 2 trial in South Africa showed the vaccine was also effective against a variant that first emerged there, known as B.1.351.

The Pfizer-BioNTech and Moderna vaccines have shown potential in lab tests against the variants, which are believed to spread more easily and may cause more serious illness. However, the trials that led to those vaccines being approved were completed before the variants had been identified.

More than half the COVID-19 cases identified in Novavax's British trial were the B.1.17 variant and 90 per cent of the cases in South Africa were B.1.351.

Novavax is also in the midst of a big trial in the United States, but a spokeswoman told The Canadian Press safety results are not expected for at least another month.

The federal department of Innovation, Science and Economic Development and the National Research Council have been in talks with all the front-running vaccine makers in the world for months, trying to lure at least one of them to make some of their vaccines at the new facility, which is on track to be finished this summer.

None of those talks have borne any fruit until now.

Opposition leaders welcomed the news but said the government needs to be far more transparent about this deal, what negotiations are underway with other manufacturers, and when these vaccines will start to be delivered from the Canadian plant.

"Canadians should know when things are going to get better," Conservative Leader Erin O'Toole said in a statement.

NDP Leader Jagmeet Singh urged the Liberals to make public all the vaccine contracts with the seven companies with which Canada has a deal to buy COVID-19 vaccines.

"This is a good step forward but it is very late," said Singh. "This is something that should have been secured a long time ago. It would have addressed a lot of the insecurity people are feeling about not getting the vaccine and seem delays in the rollout, because of production delays."

The National Research Council was even rebuffed in offers early on to help all leading vaccine makers do research on scaling up their production processes to make the precious doses as fast as possible.

None of those offers was accepted, including one with Novavax that fell apart at the 11th hour last fall.

An email chain, released to the House of Commons health committee as part of a new batch of documents on Canada's pandemic response, shows a reference to the agreement was deleted from the memorandum of understanding with Novavax to buy its vaccine the day before the vaccine purchase deal was made public.

The National Research Council was also going to make doses of CanSino Biologic's vaccine, in a deal that included a $44-million upgrade of the NRC's Royalmount facility in Montreal.

But Canada's partnership with CanSino fell apart almost as quickly as it began, when China refused to allow any doses of the vaccine to be exported to Canada for use in a clinical trial here.

The vaccine is made using technology that was developed at the NRC and then licensed to CanSino for use in an Ebola vaccine.

After that deal fell apart, the Trudeau Liberals added $126-million for the NRC to not only expand the Royalmount facility, but also build an entirely new production site beside it capable of pumping out two million doses of vaccine a month.

It won't be able to produce the cutting-edge messenger RNA vaccines, like those from Pfizer-BioNTech and Moderna, but can make most other types of vaccines. Once the deal is finalized, Novavax will have to transfer its technology to the NRC, which can then begin scaling up production.

Canada invested another $173 million in Quebec's Medicago to push research on its vaccine and build a new production plant in Quebec. If Medicago's vaccine turns out to be safe and effective for COVID-19, it will initially be made in North Carolina.

Canada's only vaccine production exists with Sanofi in Toronto and GlaxoSmithKline in Quebec. Sanofi pumps out millions of doses of vaccine in Toronto for diseases like whooping cough, polio and tetanus, while GSK's Quebec plant is where Canada gets most of its annual flu vaccine.

The two are collaborating on a COVID-19 vaccine, which was delayed until at least the fall after initial results were not as good as hoped. But their plan, like that of Pfizer, Moderna, Novavax and Johnson and Johnson, does not involve making any of that vaccine in Canada.

Canada used to have a strong domestic vaccine industry. Federal records show in 1973, Canada relied on imports for only about one-fifth of its domestic pharmaceutical requirements including both vaccines and therapeutic drugs. 

But the industry began to dry up in the 1980s, with multiple firms closing their Canadian operations, including AstraZeneca, Bristol Myers and Johnson and Johnson.

Today, Canada relies on imports for at least 85 per cent of the vaccines and other pharmaceuticals it uses.

This report by The Canadian Press was first published Feb. 2, 2021.

Mia Rabson, The Canadian Press

Note to readers: This is a corrected story. A previous version said the federal government was spending $123 million to build a new vaccine production facility in Montreal.

 
 

 

  • Like 1
  • Thanks 1
  • Cheers 1
  • Vintage 1
Link to comment
Share on other sites
thedestroyerofworlds Canucks Star

thedestroyerofworlds

Posted
Posted
33 minutes ago, gurn said:

Canada,  helping rebuild the vaccine industry at home:

https://www.msn.com/en-ca/news/canada/canada-signs-deal-with-novavax-to-make-its-covid-19-vaccine-at-new-montreal-facility/ar-BB1djn32?ocid=msedgntp

 

 

33 minutes ago, gurn said:

Canada used to have a strong domestic vaccine industry. Federal records show in 1973, Canada relied on imports for only about one-fifth of its domestic pharmaceutical requirements including both vaccines and therapeutic drugs. 

But the industry began to dry up in the 1980s, with multiple firms closing their Canadian operations, including AstraZeneca, Bristol Myers and Johnson and Johnson.

 

 
 

 

For all those complaining that Canada doesn't have vaccine production.  

  • Cheers 1
Link to comment
Share on other sites
thedestroyerofworlds Canucks Star

thedestroyerofworlds

Posted
Posted

Remember the issue where the "half dose" increased efficacy?  Turns out it has more to do with the timing of the dose.  It seems that this may have something to do with the use of an adenovirus vector.  This also will help with shortages as there will be longer wait times for the second dose.

 

New AstraZeneca Study Data: Vaccine efficacy after a single standard dose of vaccine from day 22 to day 90 post vaccination was 76%; Higher efficacy with longer wait between first and second doses

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3777268

Single Dose Administration, And The Influence Of The Timing Of The Booster Dose On Immunogenicity and Efficacy Of ChAdOx1 nCoV-19 (AZD1222) Vaccine

Link to comment
Share on other sites
thedestroyerofworlds Canucks Star

thedestroyerofworlds

Posted
Posted

Reading this, I have ZERO patience for any anti-vaxxer bull%$^.  NONE.  This article shows that no matter what you do to demonstrate that the anti-vaxxer is incorrect, they will continue to push their bull@#$*.

 

 

https://www.independent.co.uk/news/world/americas/nurse-coronavirus-vaccine-tiffany-dover-anti-vaxxers-b1795800.html?utm_source=reddit.com

Nurse who fainted during Covid vaccine harassed by anti-vaxxers wrongly convinced she’s dead

 

Tiffany Dover explained fainting is quite common for her after the incident

  • Cheers 2
Link to comment
Share on other sites
thedestroyerofworlds Canucks Star

thedestroyerofworlds

Posted
Posted (edited)

Posted earlier about how the rollout and how early results were reported tainted things.  Turns out, that this is a decent vaccine.  If the Russians didn't jump the gun, releasing the vaccine early and if the Russians didn't mess with the early reporting of the efficacy, then there would be a lot more trust in this vaccine.  (posted earlier in this tread bout the early issues with this vaccine).

 

 

Study here: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00234-8/fulltext

 

https://www.pbs.org/newshour/world/russias-sputnik-v-vaccine-appears-safe-and-effective-study-says

Russia’s Sputnik V vaccine appears safe and effective, study says

Edited by thedestroyerofworlds
Link to comment
Share on other sites

Please sign in to comment

You will be able to leave a comment after signing in



Sign In Now
 Share
Go to topic listing

  • Recently Browsing   0 members

    • No registered users viewing this page.
×
×
  • Create New...